hrp0092lb-26 | Late Breaking Posters | ESPE2019

Dramatic Clinical Response to Lenvatinib in One Pediatric Patient with Advanced Metastatic Papillary Thyroid Carcinoma

Dujovne Noelia , Gazek Natalia , Pitoia Fabian , Ayarzabal Victor , Felipe Laura , Lopez Marti Jessica , Herzovich Viviana

Papillary thyroid cancer (PTC) is the most common thyroid tumor in childhood and adolescence. Most of these patients are referred with locally advanced and/or distant disease at the moment of diagnosis. Whenever is possible, these patients should be offered a total thyroidectomy and radioiodine remnant ablation. However, this approach is not always possible to perform, becoming these tumors as unresectable. These critical cases could benefit from the neoadjuvant treatment with...

hrp0084p3-1176 | Thyroid | ESPE2015

Graves’ Disease in Childhood and Adolescence: Clinical Manifestations, Adverse Effects, and Predictive Factors for Response to Antithyroid Drugs

Dujovne Noelia Vanesa , Dratler Gustavo , Pitoia Fabian , Felipe Laura , Ayarzabal Victor , Soria Ianina , Berger Malena , Belgorosky Alicia , Herzovich Viviana

Background: Antithyroid drugs (ATD) are recommended as the initial treatment in Graves disease in childhood and adolescence. Identification of predictive factors might lead to improve patient management by facilitating the identification of patients requiring long-term ATD or early alternative therapy.Objective and hypotheses: To assess the prevalence of signs and symptoms of hyperthyroidism in childhood and adolescence, to evaluate the rates of adverse ...